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Antioxidants and Ageing -
The Opinions Of Scientists
As long ago as 1956, the research scientist D. Harmon,
writing on a medical journal devoted to the science of ageing, the
Journal of Gerontology suggested that free radicals are probably
involved in the ageing process. Since then the free radical theory of
ageing has become widely accepted. Gerontologiest now generally
believe that free radial damage to tissues is a central factor in the
development of most of the age-related diseases atherosclerosis.,
arthritis, loss of muscle an heart efficiency, cataract, rheumatoid
arthritis, lung disorders, skin deterioration and probably cancer.
Earl R. Stadtman, Chief of the Biochemistry Laboratory at the National
Heart, Lung, and Blood Institute, National Institutes of Health,
Bethesda, Maryland, writing in Science the American equivalent of
the British Nature in August 1992, summarized the current scientific
views on free radical oxidation of proteins and ageing. He confirmed
the general opinion that free radicals are responsible for much damage
to cell membranes and DNA, and described in detail the way proteins
the essential building materials of the body are attacked by
hydroxyl radicals produce din the body. The evidence he
quotes suggests that anything up to 50% of the cellular protein in old
people might be present in the damaged oxidized form.
This hard-headed scientist ends the paper with the carefully
restrained statement. There is reason for hope that a pharmacological
intervention may be found to ameliorate age-related disorders. In
other words, we have reason to believe that it may become possible to
reduce many of the effects of ageing by taking antioxidant vitamins
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